Deciphering the Immune Evolution Landscape of Multiple Myeloma Long-Term Survivors Using Single Cell Genomics
Manuscripts
Cell-DRL: Reconstructing Causal Disease Trajectories by Deep Reinforcement Learning
Abdelrahman Mahmoud and Dominic Grün
(in preparation)
Selective Elimination of Immunosuppressive T cells in Patients with Multiple Myeloma
Mohamed H.S. Awwad, Abdelrahman Mahmoud, Heiko Bruns, Hakim Echchannaoui, Katharina Kriegsmann, Marc S. Raab, Uta Bärtsch, Markus Munder, Anna Jauch, Katja Weisel6, Hans Jürgen Salwender, Volker Eckstein, Mathias Hänel, Roland Fenk, Jan Dürig, Benedikt Brors, Carsten, Müller-Tidow, Hartmut Goldschmidt, Michael Hundemer
(2020, Leukemia journal )
AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer
Varga, Julia, Adele Nicolas, Valentina Petrocelli, Marina Pesic, Abdelrahman Mahmoud, Birgitta E. Michels, Emre Etlioglu, Diego Yepes, Björn Häupl, Paul K. Ziegler, Katrin Bankov, Peter J. Wild, Stefan Wanninger, Hind Medyouf, Henner F. Farin, Sabine Tejpar, Thomas Oellerich, Jürgen Ruland, Christian W. Siebel, Florian R. Greten
(2020, Journal of Experimental Medicine journal)
CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of nichederived SPARC
Tirado-Gonzalez, I., E. Czlonka, A. Nevmerzhitskaya, D. Soetopo, E. Bergonzani, A. Mahmoud, A. Contreras, I Jeremias, U Platzbecker, J P Bourquin, U Kloz, F Van der Hoeven, H Medyouf
(2018, Leukemia journal)
Gut microbiome alterations in patients with stage 4 hepatitis C
Abdelrahman Mahmoud, Abdelreheem Adel, Ahmed Osama El-Gendy, Tamer M. Essam and Ramy K. Aziz
(2016, BMC Gut Pathogens journal)
Abstracts
The Bone Marrow Microenvironment of Multiple Myeloma Long-Term Survivors at Single Cell Resolution
Raphael Lutz*, Abdelrahman Mahmoud*, Mohamed H.S. Awwad, Charles Imbusch, Tobias Boch, Niels Weinhold, Marc S. Raab, Carsten Müller- Tidow, Brian Durie, Simon Haas, Hartmut Goldschmidt, Benedikt Brors, and Michael Hundemer
(2020, The 62nd ASH Annual Meeting and Exposition)
Deconvolution of Hematopoietic Commitment Decisions by Genome-Wide Analysis of Progressive DNA Methylation Changes
Sina Staeble, MSc, Stephen Kraemer, MSc, Jens Langstein, MSc, Ruzhica Bogeska, PhD, Mark Hartmann, PhD, Maximilian Schoenung, MSc, Melinda Czeh, PhD, Julia Knoch, Natasha Anstee, PhD, Simon Haas, PhD, Abdelrahman Mahmoud, PhD , Julius Graesel, MSc, Daniel Huebschmann, MD PhD, Lars Feuerbach, PhD, Weichenhan Dieter, PhD, Benedikt Brors, PhD, Karsten Rippe, PhD, Jan-Philipp Mallm, PhD, Frank Rosenbauer, PhD, Christoph Plass, PhD, Matthias Schlesner, PhD, Michael D. Milsom, PhD, Daniel B. Lipka
(2019, Blood Journal)